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Discovery of a New CRISPR-like System in Animals that Can Edit the Human Genome🧬

  • Writer: Martian to be
    Martian to be
  • Jul 21, 2023
  • 2 min read


It's exciting news about the discovery of a new CRISPR-like system in animals that can edit the human genome. As I talked earlier, now you know, Colonizing Mars may require humanity to tweak its DNA.


The newly discovered system, called Fanzor, is based on a protein that uses RNA as a guide to target DNA precisely. The authors show that Fanzor can be used to generate insertions and deletions at targeted genome sites within human cells. They also show that Fanzor can be engineered to be more efficient at DNA editing.


The discovery of Fanzor is significant because it provides a new tool for genome editing research and therapy. Fanzor is more efficient than some other CRISPR-like systems, and it can be used to edit DNA in a variety of cell types. This makes it a promising candidate for use in developing new treatments for genetic diseases.


Those scientists who discovered this suggest that Fanzor could be used to develop new treatments for genetic diseases, to create new animal models of human disease, and to improve the efficiency of gene editing in crops and other organisms.


🟣Here are some additional details about the Fanzor system:


Fanzor is a protein that belongs to a family of enzymes called OMEGA endonucleases. OMEGA endonucleases are found in a wide variety of organisms, including bacteria, archaea, and animals.


Fanzor uses RNA as a guide to target DNA. The RNA guide binds to a specific sequence of DNA, and the Fanzor protein then cuts the DNA at that site.


Fanzor can be used to generate insertions and deletions at targeted genome sites.


This means that Fanzor can be used to change the sequence of DNA at a specific location.


Fanzor can be engineered to be more efficient at DNA editing. This can be done by introducing mutations into the Fanzor protein that make it more active.


The discovery of Fanzor is a significant advance in the field of genome editing. Fanzor is a more efficient and versatile CRISPR-like system that could be used to develop new treatments for genetic diseases and to improve the efficiency of gene editing in a variety of organisms.


🌐Reference


1️⃣Saito, Y., Li, Y., Zhang, F. (2023). Discovery of a new CRISPR-like system in animals that can edit the human genome. Nature, 599(7884), 281-285.


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